OBJECTIVE Urinary tract conditions have been an important part of diseases from antiquity until today. Historically, many plants and herbs have been used for the treatment of urinary disorders. METHODS Celâlüddîn Hızır bin Ali el-Konevi (Hadji Pasha) is one of the most famous physician who lived in Anatolia between 13th and 14th centuries. He has written one of the most important medical book...

Objective: Urinary tract conditions have been an important part of diseases from antiquity until today. Historically, many plants and herbs have been used for the treatment of urinary disorders. Methods: Celâlüddîn Hızır bin Ali el-Konevi (Hadji Pasha) is one of the most famous physician who lived in Anatolia between 13th and 14th centuries. He has written one of the most important medical book...

Canonical primary microRNA (miRNA) transcripts and mirtrons are proposed to transit distinct nuclear pathways en route to generating mature approximately 22 nucleotide regulatory RNAs. We generated a null allele of Drosophila pasha, which encodes a double-stranded RNA-binding protein partner of the RNase III enzyme Drosha. Analysis of this mutant yielded stringent evidence that Pasha is essenti...

Drosha is a type III RNase, which plays a critical role in miRNA biogenesis. Drosha and its double-stranded RNA-binding partner protein Pasha/DGCR8 likely recognize and cleave miRNA precursor RNAs or pri-miRNA hairpins cotranscriptionally. To identify RNAs processed by Drosha, we used tiling microarrays to examine transcripts after depletion of drosha mRNA with dsRNA in Drosophila Schneider S2 ...

the metamorphic complexes of south iran (namely sirdjan, hadji-abad and dolat-abad) are conspicuously related to two different cycles of orogeny and metamorphism . these two cycles are distinctly separate and have been mapped as such throughout the hadji - abad area . the older phase is definitely pre-cambrin, whereas the younger is considered to be early - kimmerian .

The Program Archive on Sexuality, Health & Adolescence (PASHA) identifies programs aimed at preventing pregnancies and sexually transmitted diseases among teenagers, and makes materials from interventions with demonstrated effectiveness available to practitioners around the country. With the assistance of a panel of experts, PASHA has identified an initial group of 15 pregnancy prevention and 1...

The microRNA (miRNA) processing pathway produces miRNAs as posttranscriptional regulators of gene expression. The nuclear RNase III Drosha catalyzes the first processing step together with the dsRNA binding protein DGCR8/Pasha generating pre-miRNAs [1, 2]. The next cleavage employs the cytoplasmic RNase III Dicer producing miRNA duplexes [3, 4]. Finally, Argonautes are recruited with miRNAs int...

So the story goes, in the late 1980s, the Turkish general Kenan Evren, who led the 1980 coup d’etat in Turkey, encountered the popular Turkish music icon known widely as ‘the Pasha of Art’, Zeki Müren, who was a much respected performer – well-known for his extravagant costumes on stage and his mannered queer performance. This encounter was followed by a conversation initiated by the general’s ...

mirza malkum khan nazem al-dowleh, the famous iranian thinker and politician of the nineteenth century, spent about ten years in the ottoman empire during the period of tanzimat and was associated with important figures in tanzimat and the first ottoman constitutional era such as foad pasha, aali pasha and medhat pasha. later, he claimed that he had written the important tanzimats figure, foad ...